ABSTRACT
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an etiologic agent of the respiratory disease in humans known as coronavirus disease 2019 (COVID-19). The beginning of the outbreak of the disease was initially reported in Wuhan, Hubei Province, China, in December 2019, where patients felt SARS pneumonia-like symptoms with unknown etiology. Since then, it has been noticed that SARS-CoV-2 positive patients show mild to severe upper respiratory ill-ness.SARS-CoV-2 belongs to the class of Coronavirus, which is known to make its transfer from animals to humans and for the concerned virus;investigators have claimed its origin from bat coro-navirus at whole-genome level with a 96% sequence identity. The COVID-19 virus is extremely contagious and communicable in nature and has spread across the world since its first outbreak doc-umented in Wuhan, China. On March 9, 2020, World Health Organization (WHO) declared it as a pandemic, and within a month, it was already reported to have shown its presence in 213 countries and territories or areas. As of Nov15, 2020, this novel virus has infected approximately. 53.7 million people and caused 1.3 million mortalities worldwide. However, the mortality rate varied between 3-13% and was influenced by a number of factors, including the demographic distribution and maybe age, comorbidities, etc. Diagnosis of the disease is a key component of controlling the spread of the virus, and several techniques, including RT-PCR, ELISA, and sequencing-based ap-proaches, are in use. To cure COVID-19 patients, as of now, we do not have any safe and effective treatment. Currently, there is no safe and effective drug for the disease. Furthermore, various pharmaceutical industries are working on vaccine developments, which are in progress with the final stages of clinical studies. Therapeutic options are also currently under investigation in various re-gions of the world. However, there are various potential therapeutic targets to repurpose the present antiviral therapy for developing potential interventions against SARS-CoV-2 infection. Boosting the immune system can also help to prevent the spread of COVID-19 using various medications and exercises. Here, this review summarizes and discusses the epidemiology, evolution, transmis-sion, and therapeutics scientific advancements related to this novel pandemic.Copyright © 2021 Bentham Science Publishers.
ABSTRACT
chronic health risks have risen among young individuals due to several factors such as sedentary lifestyle, poor eating habits, sleep irregularities, environmental pollution, workplace stress etc. The problem seems to be more menacing in the near future, with the exacerbation of lifestyle conditions and unforeseen breakout of pandemics such as COVID-19. One possible solution is thus to design health risk prediction systems which can evaluated some critical features of parameters of the individual and then be able to predict possible health risks. As the data shows large divergences in nature with non-correlated patterns, hence choice of machine learning based methods becomes inevitable to design systems which can analyze the critical factors or features of the data and predict possible risks. This paper presents an ensemble approach for health risk prediction based on the steepest descent algorithm and decision trees. It is observed that the proposed work attains a classification accuracy of 93.72%. A simple graphic user interface has also been created for the ease of use and interaction and for prototype testing. © 2022 IEEE.
ABSTRACT
Wound Care is very important in this COVID-19 pandemic. The factors associated with poor prognosis from COVID-19 which increase the risk for chronic wounds are older age, hypertension, chronic lung disease, diabetes and obesity. Patient prioritization is a key aspect while treating wounds in patients with COVID-19 infection. Telemedicine is a supportive alternative for clinic visits and need to create awareness about use of telemedicine among the patients. The patients should be encouraged and educated about the basics of hygiene and wound care prevention.